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There are many ways giving puls therapy
d. Puls Siklofosfamid given by infusion for 1 hour with a dose of 500 mg-1, 000 mg/m2 LPB and done with organized adekuat hydration bladder frequently. Puls Siklofosfamid is given every 3 months for 4 years or until at least 18 months in remission.
e. Puls Siklofosfamid given every month for 12 months with a dose of 500 mg/m2 in the first month LPB, 750 mg/m2
LPB in the second, and a further 1000 mg / m2 LPB.
f. Siklofosfamid puls with the dose 750 mg-1, 000 mg/m2 given every month LPB to 6 months followed by a puls sikofosfamid the same dose every 3 months for 2 -3 years. Prednison given with a dose 0.5 mg / kgbb / day and then lowered slowly.
3. Metilprednisolon with siklofosfamid
a. Metilprednisolon puls 20 mg / kgbb / day given in 2 hours for 3 days. After giving intravenous metilprednisolon, carried out by intravenous hydration followed by a grant siklofosfamid LPB 500 mg/m2 plus Mesna (uromitexan) 360 mg/m2 in 100 ml LPB dekstrose 5% of each 2-hour infusion, followed by intravenous hydration. Mesna infusion given again after 2-4 hours, 6 hours and 10 hours. After metilprednisolon puls, prednison given dose 2 mg / kgbb / day and then lowered slowly. Siklofosfamid infusion given every month for six months with the dosage increased to 750-1000 mg/m2 LPB. After giving six times per month, puls siklofosfamid given every 3 months. This regimen is given in the codes of conduct lupus erythematosus Infantile systemic.
b. Metilprednisolon 30 mg / kgbb / dose given for 3 consecutive days followed by a dose of 0.5 siklofosfamid puls g/m2 LPB / dose once a month for 6 months. Prednison 2 mg / kgbb given every other day.
c. Puls cyclophosphamide at a dose of 500 mg LPB-750 mg/m2 given every month to 6 months; dose is increased to 1 g/m2 LPB for leukocytes> 3.000/mm3. Then given high doses of corticosteroids such as methylprednisolone iv Puls 1 g per day for 3 days or prednisone daily intervals; next dose lowered slowly. Patients received hydration for 24 hours before and after cyclophosphamide therapy. In addition to cyclophosphamide Puls, Puls one gives methylprednisolone with oral cyclophosphamide or chlorambucil. Puls methylprednisolone administered at a dose of 30 mg / kg / day for 3 consecutive days followed by prednisone 45 mg/m2 LPB / day and lowered slowly for 3 months, cyclophosphamide 2 mg / kg / day for 2 months, and dipiridamol 5 mg / kg / day for 6 months. Moroni et al. (1998) provide three times Puls methylprednisolone followed by oral prednisone 0.5 mg / kg / day at month 1,3, and 5 and chlorambucil 0.2 mg / kg / day in 2, 4, and 6. This regimen is given for the governance of lupus nephritis.
There are many ways giving puls therapy
d. Puls Siklofosfamid given by infusion for 1 hour with a dose of 500 mg-1, 000 mg/m2 LPB and done with organized adekuat hydration bladder frequently. Puls Siklofosfamid is given every 3 months for 4 years or until at least 18 months in remission.
e. Puls Siklofosfamid given every month for 12 months with a dose of 500 mg/m2 in the first month LPB, 750 mg/m2
LPB in the second, and a further 1000 mg / m2 LPB.
f. Siklofosfamid puls with the dose 750 mg-1, 000 mg/m2 given every month LPB to 6 months followed by a puls sikofosfamid the same dose every 3 months for 2 -3 years. Prednison given with a dose 0.5 mg / kgbb / day and then lowered slowly.
3. Metilprednisolon with siklofosfamid
a. Metilprednisolon puls 20 mg / kgbb / day given in 2 hours for 3 days. After giving intravenous metilprednisolon, carried out by intravenous hydration followed by a grant siklofosfamid LPB 500 mg/m2 plus Mesna (uromitexan) 360 mg/m2 in 100 ml LPB dekstrose 5% of each 2-hour infusion, followed by intravenous hydration. Mesna infusion given again after 2-4 hours, 6 hours and 10 hours. After metilprednisolon puls, prednison given dose 2 mg / kgbb / day and then lowered slowly. Siklofosfamid infusion given every month for six months with the dosage increased to 750-1000 mg/m2 LPB. After giving six times per month, puls siklofosfamid given every 3 months. This regimen is given in the codes of conduct lupus erythematosus Infantile systemic.
b. Metilprednisolon 30 mg / kgbb / dose given for 3 consecutive days followed by a dose of 0.5 siklofosfamid puls g/m2 LPB / dose once a month for 6 months. Prednison 2 mg / kgbb given every other day.
c. Puls cyclophosphamide at a dose of 500 mg LPB-750 mg/m2 given every month to 6 months; dose is increased to 1 g/m2 LPB for leukocytes> 3.000/mm3. Then given high doses of corticosteroids such as methylprednisolone iv Puls 1 g per day for 3 days or prednisone daily intervals; next dose lowered slowly. Patients received hydration for 24 hours before and after cyclophosphamide therapy. In addition to cyclophosphamide Puls, Puls one gives methylprednisolone with oral cyclophosphamide or chlorambucil. Puls methylprednisolone administered at a dose of 30 mg / kg / day for 3 consecutive days followed by prednisone 45 mg/m2 LPB / day and lowered slowly for 3 months, cyclophosphamide 2 mg / kg / day for 2 months, and dipiridamol 5 mg / kg / day for 6 months. Moroni et al. (1998) provide three times Puls methylprednisolone followed by oral prednisone 0.5 mg / kg / day at month 1,3, and 5 and chlorambucil 0.2 mg / kg / day in 2, 4, and 6. This regimen is given for the governance of lupus nephritis.
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