Kidney disease Proteinurik Son

In the codes of conduct various kidney disease focal segmental proteinurik as glomerulosklerosis (GSFS), nephrotic syndrome survive steroids, and others have used kortiko-steroids, siklofosfamid, klorambusil, and given an oral siklosforin in a long time with different results . Despite many reports of success, but poor for a variety of things such as irregularity take medicine, take medicine that is not continuous, or high infection display, until researchers find a treatment with better results and side effects are rare. Puls therapy (pulse therapy is one treatment option for kidney disease this proteinurik. Puls usual therapy in children is metilprednisolon and siklofosfamid. To increase the number of success, then puls therapy is usually combined with oral corticosteroids or drugs alkilating.

Puls therapy is a high dose of medication at once by way of an intravenous bolus. Literature shows that puls therapy has been used against various diseases such as Rheumatoid Vasculitis, rheumatoid arthritis, multiple sclerosis, granulomatosis Wagener, eosinofilik lung disease, idiopathic pulmonary hemosi-derosis, leukemia, and some kidney disease. Some kidney diseases of children are not responsive to oral corticosteroids and imunosupresan puls terindikasi for therapy.

In several studies proved that siklofosfamid metilprednisolon puls puls and more effective than oral siklofosfamid and high dose oral steroids induces remission and prevention of terminal renal failure with lesser side effects.